| 吡唑酸类化合物的合成研究 |
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| 引用本文： | 高宁,王元元,肖亚平.吡唑酸类化合物的合成研究[J].化学研究,2011,22(3):40-43. |
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| 作者姓名： | 高宁 王元元 肖亚平 |
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| 作者单位： | 南京师范大学化学与材料科学学院,江苏南京,210097 |
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| 摘 要： | 通过探究吡唑酸的四种不同合成方法,筛选了适合于工业化生产的合成路线;并利用农药氯虫酰胺重要中间体--3-溴-1-(3-氯吡啶-2-基)-1H-吡唑-5-甲酸的合成进行了验证,产物结构经核磁共振谱(1H NMR)确认.
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| 关 键 词： | 吡唑酸 农药 中间体 工业化 合成 |
Study on synthesis of pyrazole acids |
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| GAO Ning,WANG Yuan-yuan,XIAO Ya-ping.Study on synthesis of pyrazole acids[J].Chemical Research,2011,22(3):40-43. |
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| Authors: | GAO Ning WANG Yuan-yuan XIAO Ya-ping |
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| Institution: | (College of Chemistry and Materials Science,Nanjing Normal University,Nanjing 210097,Jiangsu,China) |
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| Abstract: | The best route to the industrialized synthesis of pyrazole acids was screened by exploring four kinds of different synthetic methods of pyrazole acids.The route was verified by successful synthesis of 3-bromo-1-（3-chloro-2-pyridinyl）-1H-pyrazole-5-carboxylic acid,an important intermediate of pesticide chlorantraniliprole.The structure of the product was confirmed by means of nuclear magnetic resonance spectroscopy（1H NMR）. |
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| Keywords: | pyrazole acid pesticide intermediate industrialization synthesis |
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