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Functional modulation of human delta opioid receptor by neuropeptide FF |
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| Authors: | Minna-Liisa??nk? |
| Institution: | (1) Department of Biology, bo Akademi University, Tykistkatu 6A, 2nd floor, Turku, FI-20520, Finland;(2) Neuroscience Center and Institute of Biomedicine/Anatomy, University of Helsinki, Haartmaninkatu 8, Helsinki, FI-00014, Finland |
| Abstract: | BackgroundNeuropeptide FF (NPFF) plays a role in physiological pain sensation and opioid analgesia. For example, NPFF potentiates opiate-induced analgesia and the delta opioid receptor antagonist naltrindole inhibits NPFF-induced antinociception. The nature of the interactions between NPFF and opioid receptors seems to be complex and the molecular mechanisms behind the observed physiological effects are not known. |
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