Screening for coumatetralyl in soft drinks by solid-matrix extraction and high-performance liquid chromatography with diode-array detection. |
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| Authors: | A Dimuccio I Camoni L Vergori R Dommarco D Attard Barbini F Vergori A Ausili A Santilio |
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| Affiliation: | Istituto Superiore di Sanità, Rome, Italy. |
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| Abstract: | A method was developed for the rapid determination coumatetralyl in cola- and orange-type soft drinks, which includes extraction using solid-matrix column, clean-up by silica cartridge chromatography and reversed-phase high-performance liquid chromatography with diode-array detection. The recovery of coumatetralyl from 50 ml of soft drinks was better than 80% at spiking levels down to 50 micrograms/kg (ppb). |
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