Effect of isomerization of amino acid residues on the structure of aquaporin |
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| Authors: | A V Dmitriev P P Isaev V A Tverdislov |
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| Institution: | (1) Lipetsk State Pedagogical University, Russia;(2) N. A. Nekrasov Kostroma State University, Russia;(3) M. V. Lomonosov Moscow State University, Russia |
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| Abstract: | The effect of isomerization of amino acid residues on the structure and water permeability of aquaporin has been investigated. It was established that the equilibrium configuration of the model D isomer is energetically less favorable than that of its natural L isomer. It is shown that the model D isomer of aquaporin is waterproof. |
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| Keywords: | aquaporin D isomer of aquaporin force field water permeability |
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