2-(<Emphasis Type="Italic">N</Emphasis>-Alkylamino)-1-(trifluoroacetimidoyl)vinyl ketone derivatives as potential reagents in heterocyclic synthesis |
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| Authors: | L S Vasil’ev M A Prezent A V Ignatenko V A Dorokhov |
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| Institution: | (1) Zhoukou Normal University, Zhoukou, Henan, People’s Republic of China;(2) Tanshan Medical University, Beijing, People’s Republic of China;(3) Beijing Institute of Biotechnology, Beijing, People’s Republic of China;(4) 307 Hospital of PLA, Beijing, People’s Republic of China; |
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| Abstract: | A reaction of 3-acetyl-4-amino-5,5,5-trifluoropent-3-en-2-one diphenylboron chelate and ammonia or primary amines affords
4-amino- or 4-alkylamino-3-trifluoroacetimidoylpent-3-en-2-ones, new reagents which can be used for the synthesis of pyrimidines
with trifluoromethyl group. |
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