首页 | 本学科首页   官方微博 | 高级检索  
     检索      


Enzyme-linked immunosorbent assay for detection of organophosphorylated butyrylcholinesterase: a biomarker of exposure to organophosphate agents
Authors:Wang Limin  Du Dan  Lu Donglai  Lin Chiann-Tso  Smith Jordan N  Timchalk Charles  Liu Fengquan  Wang Jun  Lin Yuehe
Institution:Laboratory of Analytical Chemistry and Centre for Process Analytical Chemistry and Sensor Technology ProSens, ?bo Akademi University, ?bo, Finland.
Abstract:Lowering of the detection limit of solid-state lead-selective electrodes was achieved by using the tuned galvanostatic polarization method. A Nernstian response was obtained down to nanomolar concentrations (low detection limit 10(-9) mol dm(-3)Pb(2+)). Good repeatability of the calibration curves was achieved by using a well established measuring procedure. Relatively high cathodic current densities were applied to the solid-state membrane in order to shorten the measurement time. Successful determination of lead in a synthetic sample (pPb(2+)=7.97±0.08) was achieved by introducing an analytical protocol and favourably compared to inductively coupled plasma mass spectrometry (pPb=7.93). By applying this method, a significant improvement in the detection limit of solid-state lead-selective electrodes was attained.
Keywords:
本文献已被 PubMed 等数据库收录!
设为首页 | 免责声明 | 关于勤云 | 加入收藏

Copyright©北京勤云科技发展有限公司  京ICP备09084417号