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Studies of the influence of hydrogen chloride on the liquid chromatographic properties of amino bonded phases
Authors:S B Ehtesham  R K Gilpin
Institution:(1) Department of Chemistry, Kent State University, 44242 Kent, OH, USA
Abstract:Summary The influence of hydrogen chloride on the retention properties of aminopropyl bonded phases is studied using a series of simple aromatics, phenols and acids. The result of the HCL treatment is to mediate the hydrogen bonding interaction between the solute's polar functional groups and the bound amino groups.
Keywords:Column liquid chromatography  Amino bonded phases  Hydrogen chloride treatment  Retention anomalies  Normal-phase separations
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