Synthesis of imidazolidin-2-one-4-carboxylate and of (tetrahydro)pyrimidin-2-one-5-carboxylate via an efficient modification of the Hofmann rearrangement |
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| Authors: | Angelici Gaetano Contaldi Simone Green Sarah Lynn Tomasini Claudia |
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| Institution: | Dipartimento di Chimica G. Ciamician-Alma Mater Studiorum, Università di Bologna, Via Selmi 2, 40126 Bologna, Italy. |
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| Abstract: | A mild and efficient methodology for the rearrangement of protected asparagine and protected glutamine is reported; good results are obtained with a wide selection of protecting groups. |
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