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Designing label-free DNA sequences to achieve controllable turn-off/on fluorescence response for Hg2+ detection
Authors:Zhu Zece  Xu Liang  Zhou Xiang  Qin Jingui  Yang Chuluo
Institution:Department of Chemistry, Wuhan University, Wuhan 430072, China.
Abstract:Controllable turn off/on fluorescent sensors for Hg(2+) detection were developed by designing different label-free DNA sequences and using the minor groove dye of DAPI. These assays exhibit high sensitivity and selectivity, with the detection limits of 5 nM and 1.5 nM for turn off and turn on sensors, respectively.
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