Isatin‐1,2,3‐triazole‐isatin Scaffolds and Their Antibacterial Activity

Twelve novel isatin‐1,2,3‐triazole‐isatin scaffolds 5a – l were designed, synthesized, and assessed for their in vitro antibacterial activity in this paper. The preliminary results showed that all dimers only endowed with weak antibacterial activity, which was less active than the reference ciprofloxacin. However, the structure–activity relationship was enriched, which may be useful for the further development of more efficient candidates.