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Synthesis and anti‐inflammatory effect of morachalcone B,morachalcone C,and analogs
Authors:Bo‐Syuan Jhong  Ting‐Yu Lin  Chien‐Hsiang Kao  Hsi‐Jung Yu  Tsung‐Mei Chin  Ching‐Yang Liu  Yuh‐Chiang Shen  Ming‐Jaw Don
Abstract:An efficient method to synthesize morachalcones B and C ( 1 and 2 ) is described. Rap?Stoermer condensation and 1,3‐prenyl rearrangement were used as two key synthetic methods. Morachalcone C was obtained by photo‐oxygenation of morachalcone B. Morachalcones B and C showed moderate anti‐inflammatory activity.
Keywords:anti‐inflammatory activity  morachalcone B  morachalcone C  Rap−  Stoermer condensation
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