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Tuning a Bisphenol A Lateral Flow Assay Using Multiple Gold Nanosystems
Authors:Li‐Kai Lin  Peng‐Yuan Huang  Sayan Dutta  Jean‐Christophe Rochet  Lia A. Stanciu
Abstract:Advanced bisphenol A (BPA) lateral flow assays (LFAs) that use multiple nanosystems are reported. The assays use three nanosystems: gold nanostars, gold nanocubes, and gold nanorods, which are rarely applied in LFAs, compared with general gold nanoparticles that are referred to as gold nanospheres in this paper. These various nanosystems are bound to anti‐BPA antibodies and applied in LFAs to develop advanced BPA LFAs; the developed LFAs show differing BPA detection performance, as well as different visible colors, optical intensities, limits of detection, and application ranges. Advanced BPA LFAs that use multiple gold nano‐object shapes are successfully developed, and the geometry effects of diverse gold nanosystems coupled with anti‐BPA antibodies and the potential applications of regular BPA LFAs are explored.
Keywords:bisphenol A  gold structures  lateral flow assays
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