Microwave Synthesis of Fused Pyrans by Humic Acid Supported Ionic Liquid Catalyst and Their Antimicrobial,Antioxidant, Toxicity Assessment,and Molecular Docking Studies |
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Authors: | Muthu Thangaraj Bibhuti Ranjan Ramesh Muthusamy Arul Murugesan Robert Moonsamy Gengan |
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Abstract: | A series of fused quinolinyl and quinolonyl pyrans were synthesized via a one‐pot reaction of quinolinyl and quinolonyl carbaldehydes, malononitrile, and a 1,3‐diketone. The reactions were catalyzed by a new humic acid supported 1‐butyl‐3‐methyl imidazolium thiocyanate ionic liquid under microwave irradiation conditions. Antimicrobial, antioxidant, and toxicity studies displayed various biological activities depending on structure of the pyrans. |
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