首页 | 本学科首页   官方微博 | 高级检索  
     检索      


NHC/Nickel(II)‐Catalyzed [3+2] Cross‐Dimerization of Unactivated Olefins and Methylenecyclopropanes
Authors:Jian‐Qiang Huang  Chun‐Yu Ho
Abstract:Cross‐dimerization of a methylenecyclopropane ( 1 ) and an unactivated alkene ( 2 ) with typical hydroalkenylation reactivity was observed for the first time by using a NHC‐Ni(allyl)]BArF catalyst (NHC=N‐heterocyclic carbene). Results show that the C?C cleavage of 1 did not involve a Ni0 oxidative addition, which was crucial in former systems. Thus the method reported here emerges as a complementary method for attaining highly chemo‐ and regioselective synthesis of methylenecyclopentanes ( 3 ) with broad scope. An efficient NHC/NiII‐catalyzed rearrangement of 1 leads to the convergent synthesis of 3 in the presence of 2 .
Keywords:alkenes  hydroalkenylation  insertion  N-heterocyclic carbenes  nickel
设为首页 | 免责声明 | 关于勤云 | 加入收藏

Copyright©北京勤云科技发展有限公司  京ICP备09084417号