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Synthesis and Antinociceptive Activity of N -Substituted 4-Aryl-4-oxo-2-[(3-thiophen-2-yl)amino]but-2-enamides |
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| Authors: | S A Shipilovskikh V Y Vaganov R R Makhmudov A E Rubtsov |
| Abstract: | 2-{5-Aryl-2-oxofuran-3(2H)-ylidene]amino}thiophene-3-carboxylic acid derivatives reacted with substituted amines to give new N-substituted 4-aryl-4-oxo-2-(3-thiophen-2-yl)amino]but-2-enamides. Antinociceptive activity of the synthesized compounds was studied. |
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