The design of TOPK inhibitors using structure-based pharmacophore modeling and molecular docking based on an MD-refined homology model |
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| Authors: | Fakhouri Lara I. Al-Shar’i Nizar A. |
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| Affiliation: | 1.Department of Medicinal Chemistry and Pharmacognosy, Faculty of Pharmacy, Jordan University of Science and Technology, P.O. Box 3030, Irbid, 22110, Jordan
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| Abstract: | Molecular Diversity - The TOPK enzyme (also known as PBK) is a serine-threonine protein kinase that is rarely detected in normal tissues yet is found to be overexpressed and activated in a variety... |
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