Synthesis, 99mTc-labeling,in-vivo study and in-silico investigation of 6-amino-5-[(bis-(2-hydroxy-ethyl)-amino]methyl]2-methyl pyrimidin-4-ol as a potential probe for tumor targeting |
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Authors: | Essa Basma M Abd-Allah Walaa H Sakr Tamer M |
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Institution: | 1.Radioactive Isotopes and Generators Department, Hot Laboratories Center, Egyptian Atomic Energy Authority, Cairo, 13759, Egypt ;2.Pharmaceutical Chemistry Department, College of Pharmaceutical Sciences and Drug Manufacturing, Misr University for Science & Technology, Giza, Egypt ; |
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Abstract: | Journal of Radioanalytical and Nuclear Chemistry - This study aimed to synthesize a new pyrimidine derivative with a good synthesis yield of 87% to act as a new cancer marker after radiolabeling... |
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