| 反胶团相转移法提取青霉素G的研究 |
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| 引用本文： | 吴子生 贾颖萍. 反胶团相转移法提取青霉素G的研究[J]. 高等学校化学学报, 1993, 14(10): 1427-1431 |
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| 作者姓名： | 吴子生 贾颖萍 |
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| 作者单位： | 东北师范大学化学系，大连大学师范学院化学系，东北师范大学化学系，东北师范大学化学系，东北师范大学化学系，东北师范大学化学系 长春 130024，长春 130024，长春 130024，长春 130024，长春 130024 |
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| 摘 要： | 报道了非蛋白质类活性物质青霉素Ｇ在反胶团相转移提取中的特性和机理。结果表明，青霉素Ｇ在ＣＴＡＢ／正辛醇：氯仿（４：１，Ｖ／Ｖ）反胶团体系中的相转移提取为离子对静电作用与胶团溶解机理；在室温及ｐＨ值５～８的条件下，提取率在９０％以上，且保持了青霉素的稳定性。
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| 关 键 词： | 反胶团相转移 青霉素G 提取 |
Studies on the Phase Transfer Extraction of Penicillin G by Reverse Micelles |
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| WU Zi-Sheng,JIA Ying-Ping,CHU Ying,WANG Yu-Jie,LIU PeiYan,MA Zhan-Fang. Studies on the Phase Transfer Extraction of Penicillin G by Reverse Micelles[J]. Chemical Research In Chinese Universities, 1993, 14(10): 1427-1431 |
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| Authors: | WU Zi-Sheng JIA Ying-Ping CHU Ying WANG Yu-Jie LIU PeiYan MA Zhan-Fang |
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| Abstract: | This paper reports the extraction properties and mechanisms of a non-protein active matter penicillin G by reverse micelles using the phase transfer technique for the first time. It is shown that the mechanisms of the phase transfer extraction of penicillin G using CTAB/n-octanol : chloroform(4 : 1) reverse micellar system are ion-pairing electrostatic interactions and micellar solubilisation. It is also shown that the extraction is above 90% in the pH range from 5 to 8 in which penicillin G is stable at room temperature. |
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| Keywords: | Reverse micelle Phase transfer Penicillin G |
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