Chemical synthesis of oligoribonucleotides containing 2-aminopurine: substrates for the investigation of ribozyme function |
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| Authors: | Doudna J A Szostak J W Rich A Usman N |
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| Institution: | Department of Biology, Massachusetts Institute of Technology, Cambridge 02139, USA. |
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| Abstract: | The chemical synthesis of a fully protected ribonucleoside phosphoramidite, containing 2-aminopurine as the base component, and its incorporation into short oligoribonucleotides as substrates for an engineered ribozyme from Tetrahymena is described. |
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