Naucleamides A-E,new monoterpene indole alkaloids from Nauclea latifolia |
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| Authors: | Shigemori Hideyuki Kagata Toshinori Ishiyama Haruaki Morah Frank Ohsaki Ayumi Kobayashi Jun'ichi |
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| Institution: | Graduate School of Pharmaceutical Sciences, Hokkaido University, Sapporo, Japan. |
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| Abstract: | Five new monoterpene indole alkaloids, naucleamides A-E (1-5), were isolated from the bark and wood of Nauclea latifolia, and the structures and relative stereochemistry were elucidated from the spectroscopic data. Naucleamide E (5) is a unique monoterpene indole alkaloid possessing a pentacyclic ring system with an amino acetal bridge. |
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