Preparation of trifluoromethylated pyrazoles and 1,4-thiazine 1,1-dioxides from trifluoromethylated sulfone derivatives

Trifluoromethylated sulfones, 3-amino-2-arylsulfonyl-4,4,4-trifluoro-3-hydroxybutanenitrile ( 3 ) and 3-(aroylmethyl)sulfonyl-1,1,1-trifluoropropane-2,2,-diols 12 , were prepared and cyclized to 4-arylsulfonyl-5-trifluoromethyl-3-hydrazinopyrazoles 9 and 5-arylsulfonyl-3-trifluoromethyl-3-hydroxy-2,3-dihydro-4H-1,4-thiazine 1,1-dioxides 13 , respectively.