Intramolecular glycosylation as a regio- and stereocontrolled approach for the synthesis of 8-oxo-purine nucleosides |
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Authors: | Hideyuki Sugimura Daisuke Nitta |
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Affiliation: | Department of Chemistry and Biological Science, Aoyama Gakuin University, 5-10-1, Fuchinobe, Chuo-ku, Sagamihara-shi 252-5258, Japan |
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Abstract: | Intramolecular glycosylation of purine derivatives that are temporarily connected to the 5 position of ribofuranosyl donors at their 8 position through an ethereal linkage leads to 8-oxo-purine β-nucleosides in a stereoselective manner. |
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Keywords: | 8-Oxo-purine nucleosides Intramolecular reaction Glycosylation Stereocontrolled reaction |
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