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Intramolecular glycosylation as a regio- and stereocontrolled approach for the synthesis of 8-oxo-purine nucleosides
Authors:Hideyuki Sugimura  Daisuke Nitta
Affiliation:Department of Chemistry and Biological Science, Aoyama Gakuin University, 5-10-1, Fuchinobe, Chuo-ku, Sagamihara-shi 252-5258, Japan
Abstract:Intramolecular glycosylation of purine derivatives that are temporarily connected to the 5 position of ribofuranosyl donors at their 8 position through an ethereal linkage leads to 8-oxo-purine β-nucleosides in a stereoselective manner.
Keywords:8-Oxo-purine nucleosides   Intramolecular reaction   Glycosylation   Stereocontrolled reaction
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