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Palladium-catalysed coupling of terminal alkynes with aryl halides aided by catalytic zinc |
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| Authors: | Geoffrey T Crisp Peter D Turner Kim A Stephens |
| Affiliation: | Department of Chemistry, The University of Adelaide, Adelaide, South Australia, 5005, Australia |
| Abstract: | The palladium-catalysed coupling of aryl halides with terminal alkynes can be performed using base, zinc chloride and sodium iodide. This protocol represents a convenient method for the generation of nucleophilic acetylides in situ. |
| Keywords: | Palladium catalysis Coupling of oxyhalides with alkynes Nucleophilic alkynes |
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