a Kansai Technical Research Institute, Toppan Printing Co. Ltd., Ebie, Fukushima-ku, Osaka 553, Japan
b Research Center for Environmental Preservation, Osaka University, Yamada-oka, Suita, Osaka 565, Japan
Abstract:
The chiral separation ability of unmodified and di- and trimethylated -, β- and γ-cyclodextrins (CDs) as chiral selectors in capillary zone electrophoresis was investigated in the presence of urea derivatives using twelve dansylamino acids as model solutes. The addition of these urea derivatives (unsubstituted, methyl-, ethyl- and 1,3-dimethylureas) produced dramatic enhancement in the enantioselectivity of unmodified β-CD but also reduced the enantioselectivities of the other CDs.