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Water promoted, microwave-assisted oxidative novel deamination of N-aminoquinazolinones |
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| Authors: | M Arfan Rasool Khan Shazia Anjum Shabir Ahmad M Iqbal Choudhary |
| Institution: | a Institute of Chemical Sciences, University of Peshawar, Peshawar 25120, Pakistan;b HEJRIC, International Centre for Chemical and Biological Sciences, University of Karachi, Karachi 75270, Pakistan |
| Abstract: | A novel deamination of 2-alkyl/aryl 3-amino-4(3H)-qninazolinones series using aqueous KMnO4 under thermal condition and microwave irradiation is described.Compared to thermal condition,significantly higher yields in much shorter times were observedfor reactions under microwave irradiation.A plausible mechanism has been proposed for the oxidative water-promoted deamination. |
| Keywords: | N-Aminoouinazolinones Oxidative deamination:KMnO4 Water Microwave irradiation |
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