Conoideoxime A,antibacterial bis-oxime prenyl-tryptophan dimer from the whitefly pathogenic fungus Conoideocrella luteorostrata BCC 76664 |
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| Authors: | Masahiko Isaka Somporn Palasarn Wilunda Choowong Suchada Mongkolsamrit |
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| Institution: | National Center for Genetic Engineering and Biotechnology (BIOTEC), 113 Thailand Science Park, Phaholyothin Road, Klong Luang, Pathumthani 12120, Thailand |
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| Abstract: | Conoideoxime A (1), a prenyl-tryptophan dimer possessing bis-oxime functionality, was isolated from cultures of the whitefly pathogenic fungus Conoideocrella luteorostrata BCC 76664. The structure was elucidated by spectroscopic analyses. It displayed antibacterial activity against Gram-positive bacteria, Bacillus cereus, Enterococcus faecium, and Staphylococcus aureus, with MIC values of 3.13, 6.25, and 6.25?μg/mL, respectively. |
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| Keywords: | Insect pathogenic fungi Oxime Prenylated tryptophan Antibacterial activity |
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