Controllable shape selectivity based on highly ordered carbonyl and methyl groups in simple β-structural polypeptide on silica |
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| Authors: | Atsuomi Shundo Abul K Mallik Toshihiko Sakurai Makoto Takafuji Shoji Nagaoka Hirotaka Ihara |
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| Institution: | 1. Department of Applied Chemistry and Biochemistry, Kumamoto University, 2-39-1 Kurokami, Kumamoto 860-8555, Japan;2. Kumamoto Industrial Research Institute, 3-11-38 Higashi-machi, Kumamoto 862-0901, Japan |
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| Abstract: | Poly(l-alanine)-grafted porous silica (Sil-Ala22) was prepared by polymerization of N-carboxyanhydride of l-alanine initiated by 3-aminopropylated silica. The retention behaviors of the column packed with Sil-Ala22 were investigated by using alkylbenzenes and polycyclic aromatic hydrocarbons as injection samples in liquid chromatography. The Ala22 phase was in a rigid β-form structure and thus provided specific interaction sites, which were derived from the highly ordered carbonyl and methyl groups. These interaction sites bring unique molecular-shape discriminations: molecular-length and non-planarity selectivity, which are controllable by altering organic solvent used as a part of mobile phase. |
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| Keywords: | Alanine β-Structure Non-planarity recognition Polycyclic aromatic hydrocarbons π&ndash π interaction Liquid chromatography |
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