Syntheses of some new 4-amino-5-(N-methyl-arylsulfonamido)methyl-1,2,4-triazole-3-thiones and their derivatives |
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Authors: | Guofeng Jia Zhengming Li |
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Abstract: | The cyclization of 4-amino-5-(N-methyl-arylsulfonamido)methyl-1,2,4-triazole-3-thiones II , synthesized by the Reid and Heindel approach, with α-chloroacetophenone yields 7II-6-aryl-3-(N-methyl-arylsulfon-amido)methyl-s-triazolo3,4-b]1,3,4]-thiazines III . Novel compounds II also react with benzyl chloride to afford 4-amino-3-benzylthio-5-(N-methyl-arylsulfonamido)methyl-1,2,4-triazole IV . © 1996 John Wiley & Sons, Inc. |
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