| LIPOGENESIS STIMULATORY AND INHIBITORY ACTIVITIES OF THE INSULIN MEDIATORS |
| |
| 引用本文： | 张世荣,乐云,姚文贞,幸兴球,韩锦华,王敬泽,郭宏亮. LIPOGENESIS STIMULATORY AND INHIBITORY ACTIVITIES OF THE INSULIN MEDIATORS[J]. 中国科学B辑(英文版), 1990, 0(1) |
| |
| 作者姓名： | 张世荣 乐云 姚文贞 幸兴球 韩锦华 王敬泽 郭宏亮 |
| |
| 作者单位： | Institute of Zoology，Academia Sinica，Beijing 100080，PRC，Institute of Zoology，Academia Sinica，Beijing 100080，PRC，Institute of Zoology，Academia Sinica，Beijing 100080，PRC，Institute of Zoology，Academia Sinica，Beijing 100080，PRC，Institute of Zoology，Academia Sinica，Beijing 100080，PRC，Institute of Zoology，Academia Sinica，Beijing 100080，PRC，Institute of Zoology，Academia Sinica，Beijing 100080，PRC |
| |
| 基金项目： | Project supported by the National Natural Science Foundation of China. |
| |
| 摘 要： | Incubating plasma membranes prepared from pig liver with varying concentrations of insulin (50—1000 μU/ml) resulted in the release of at least two insulin chemical mediators. One of them was fraction 1 of insulin mediator (M. W. 3700—4000 daltons) which had a significant lipogenesis-stimulatlug activity. The other was fraction 2 of insulin mediator (M. W. about 1000 daltons) which exhibited a lipogenesis-inhibitory activity.The ratio of yield between the two mediators produced from the membranes was not only dependent on the concentration but also on the potency of insulin and its analogs added. The result showed that there was more production of fraction 2 than fraction 1 with the inducer at low concentration (100 μU/ml), while the production of fraction 1 from the plasma membranes incubated with high concentration of insulin (300 μU/ml) was higher than fraction 2. On the other hand, insulin and its analogs which have different biological activities and receptor bindtng activities have been used t
|
LIPOGENESIS STIMULATORY AND INHIBITORY ACTIVITIES OF THE INSULIN MEDIATORS |
| |
| ZHANG SHI-RONG YUE YON YAO WEN-ZHEN XING XING-QIU HAN JIN-HUA WANG JING-ZE AND GUO HONG-LIANG. LIPOGENESIS STIMULATORY AND INHIBITORY ACTIVITIES OF THE INSULIN MEDIATORS[J]. Science in China(Chemistry), 1990, 0(1) |
| |
| Authors: | ZHANG SHI-RONG YUE YON YAO WEN-ZHEN XING XING-QIU HAN JIN-HUA WANG JING-ZE AND GUO HONG-LIANG |
| |
| Abstract: | |
| |
| Keywords: | insulin analogs insulin mediator lipogenesis. |
| 本文献已被 CNKI 等数据库收录！ |
