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Directed diversity-oriented synthesis. Ring-fused 5- to 10-membered rings from a common peptidomimetic 2-pyridone precursor |
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| Authors: | Magnus SellstedtG. Krishna Prasad K. Syam KrishnanFredrik Almqvist |
| Affiliation: | Department of Chemistry, Umeå University, 901 57 Umeå, Sweden Umeå Centre for Microbial Research, Umeå University, 901 57 Umeå, Sweden |
| Abstract: | A variety of ring-fused 2-pyridone-based central fragments were prepared using a strategy inspired by diversity-oriented synthesis. The produced compounds are diverse, yet focused, analogs of biologically active peptidomimetic 2-pyridones. |
| Keywords: | Diversity-oriented synthesis Medium-sized rings Peptidomimetics 2-Pyridone |
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