Abstract: | The dimeric sesquiterpene lactone mikagoyanolide (I) has been isolated from the plantTanacetopsis mucronata. The spatial structure of (I) has been determined by the x-ray structural method (R=0.086, 1161 reflections). The dimeric lactone is formed from cyclodecadienes of the germacrolide and melampolide types having chair-chair and boat-chair conformations. The conformational state of the free molecule of (I) has been calculated by the method of molecular mechanics.Institute of Chemistry of Plant Substances, Uzbekistan Republic of Sciences, Tashkent. Translated from Khimiya Prirodnykh Soedinenii, No. 2, pp. 213–217, March–April, 1993. |