Asymmetric pericyclic cascade approach to spirocyclic oxindoles |
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| Authors: | Richmond Edward Duguet Nicolas Slawin Alexandra M Z Lébl Tomáš Smith Andrew D |
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| Affiliation: | EaStCHEM, School of Chemistry, University of St. Andrews, North Haugh, St. Andrews, KY16 9ST, UK. |
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| Abstract: | The reaction of chiral N-arylnitrones with carbocyclic alkylarylketenes generates spirocyclic oxindoles in good yields and with excellent levels of enantioselectivity (90-99% ee) via a pericyclic cascade process. |
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