Expedient synthesis of highly substituted fused heterocoumarins |
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Authors: | Sellès P Mueller U |
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Institution: | Research Department, Lead Finding Chemistry, SYNGENTA Crop Protection AG, CH-4002, Basel, Switzerland. patrice.selles@syngenta.com |
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Abstract: | reaction: see text] Highly substituted fused coumarins can be prepared in two steps starting from the appropriate boronic acids and enol triflates. The synthesis of fused pyrano2,3-d]pyrimidin-7-one (1) is a key example to demonstrate the potential of the method in the elaboration of new coumarin scaffolds. |
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