Hard x-ray Zernike microscopy reaches 30 nm resolution |
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Authors: | Chen Yu-Tung Chen Tsung-Yu Yi Jaemock Chu Yong S Lee Wah-Keat Wang Cheng-Liang Kempson Ivan M Hwu Y Gajdosik Vincent Margaritondo G |
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Institution: | Institute of Physics, Academia Sinica, Taipei 115, Taiwan. |
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Abstract: | Since its invention in 1930, Zernike phase contrast has been a pillar in optical microscopy and more recently in x-ray microscopy, in particular for low-absorption-contrast biological specimens. We experimentally demonstrate that hard-x-ray Zernike microscopy now reaches a lateral resolution below 30 nm while strongly enhancing the contrast, thus opening many new research opportunities in biomedicine and materials science. |
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