An intermediate in a new synthesis approach to β‐substituted β‐hydroxyaspartame |
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Authors: | Johny Wehbe,Valé rie Rolland,Jean Martinez,Marc Rolland |
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Abstract: | The crystal and molecular structure of 1‐tert‐butyl 4‐ethyl (2′R,3′R,5′R,2S,3S)‐3‐bromomethyl‐3‐hydroxy‐2‐[(2′‐hydroxy‐2′,6′,6′‐trimethylbicyclo[3.1.1]hept‐3′‐ylidene)amino]succinate, C21H34BrNO6, is presented. This compound is an intermediate in the new synthetic route to β‐substituted β‐hydroxyaspartates, which are blockers of glutamate transport. |
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