Simvastatin

Simvastatin, or (1S,3R,7S,8S,8aR)‐8‐{2‐(2R,4R)‐4‐hydroxy‐6‐oxo‐3,4,5,6‐tetra­hydro‐2H‐pyran‐2‐yl]­ethyl}‐3,7‐di­methyl‐1,2,3,7,8,8a‐hexa­hydro­naphthalen‐1‐yl 2,2‐di­methyl­butan­oate, C₂₅H₃₈O₅, is almost isostructural with lovastatin, and the general conformational features are closely related to those of other reported crystal structures of statins. The only hydrogen bond present facilitates the formation of infinite chains of mol­ecules along the b axis.