Efficient asymmetric addition of diethylzinc to aldehydes using 3‐hydroxyazetidine derivatives as chiral ligands |
| |
| Authors: | Ruochen Liu Xuemei Bai Zhanbin Zhang Guofu Zi |
| |
| Institution: | Department of Chemistry, Beijing Normal University, Beijing 100875, People's Republic of China |
| |
| Abstract: | A new series of chiral 3‐hydroxyazetidines has been prepared from (S)‐1‐(4‐methoxyphenyl)ethylamine. These ligands have shown excellent catalytic activities and enantiomeric selectivities in asymmetric addition of diethylzinc to aromatic aldehydes. Copyright © 2008 John Wiley & Sons, Ltd. |
| |
| Keywords: | azetidines chiral ligands asymmetric addition diethylzinc aldehyde |
|
