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氮杂Wittig反应的最近进展
引用本文:丁明武,刘钊杰. 氮杂Wittig反应的最近进展[J]. 有机化学, 2001, 21(1): 1-7
作者姓名:丁明武  刘钊杰
作者单位:华中师范大学有机合成研究所
摘    要:综述了最近几年氮杂Wittig反应的研究进展,包括分子间氮杂Wittig反应、分子内氮杂wittig反应及串联的氮杂Wittig反应。讨论了氮杂Wittig反应在一些含氮杂环、稠杂环及天然产物合成中的应用。

关 键 词:有机合成  维蒂希反应  稠环化合物  氮杂环化合物  分子间反应  分子内反应
修稿时间:1999-11-12

Recent advances in Aza-Wittig reaction
DING ming-wu,LIU Zhao-jie. Recent advances in Aza-Wittig reaction[J]. Chinese Journal of Organic Chemistry, 2001, 21(1): 1-7
Authors:DING ming-wu  LIU Zhao-jie
Affiliation:Huazhong Normal Univ, Inst Organ Synth.Wuhan(430070)
Abstract:Recent advances in aza Wittig reaction, including intermolecular, intramolecular and tandem ones , are reviewed. The application of the aza Wittig reactions in synthesis of some N heterocycles, fused heterocycles and natural products are also discussed. Some N containing compounds not easily accessible by other methods were prepared by intermolecular aza Wittig reactions under mild neutral conditions. The efficient intramolecular aza Wittig reaction was also successively utilized in synthesis of five to eight membered heterocycles, including some optically active natural compounds. Many heterocycles, fused heterocycles and natural compounds were prepared via the versatile tandem aza Wittig reaction, such as tandem aza Wittig/heterocumulene mediated annulation, three component tandem aza Wittig reaction, tandem aza Wittig/electrocyclic ring closure, tandem aza Wittig/hetero Diels Alder closure and tandem aza Wittig reaction utilizing bis iminophosphorane.
Keywords:aza Wittig reaction   heterocyclic synthesis   review
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