Reaction of 2,3,3-trimethyl-3H-indole hydrochloride with methacrylic and crotonic amides

Reaction of 2,3,3-trimethyl-and 2,3,3,5-tetramethyl-3H-indole hydrochlorides with methacrylic and crotonic amides gives 3- and 4-methyl-1,2,3,4,10,10a-hexahydropyrimido[1,2-a]indol-2-ones. With perchloric acid these are converted to 1-carbamoylpropyl-3H-indolium perchlorates. The syntheses of 10a-(4-dimethylaminostyryl)- and 10a-[(4-dimethylaminophenyl)butadienyl]-3,10,10-trimethylpyrimido[1,2-a]indol-2-ones have been studied.Translated from Khimiya Geterotsiklicheskikh Soedinenii, No. 5, pp. 625–627, May, 1990.