| 齐墩果酸-烷醇胺复合物的制备及性能 |
| |
| 引用本文： | 闫佳文,马振毛. 齐墩果酸-烷醇胺复合物的制备及性能[J]. 应用化学, 2014, 31(7): 823-827. DOI: 10.3724/SP.J.1095.2014.30499 |
| |
| 作者姓名： | 闫佳文 马振毛 |
| |
| 作者单位： | (南京师范大学化学与材料科学学院 南京 210023) |
| |
| 基金项目： | 江苏省协同创新中心和江苏高校优势学科建设工程资助项目~~ |
| |
| 摘 要： | 采用超声法制备齐墩果酸(OA)与烷醇胺(EAs)[单乙醇胺(MEA)、二乙醇胺(DEA)或三乙醇胺(TEA)]复合物，利用差示扫描量热、X射线衍射、红外光谱和拉曼光谱等技术手段对复合物进行了表征。 发现OA与EA之间无新的化学键形成，它们以分子间力结合形成复合物。 OA与EA复合物提高了OA的溶解度，为OA新型给药系统提供新思路和理论依据。
|
| 关 键 词： | 齐墩果酸 烷醇胺 超声法 溶解度 |
| 收稿时间： | 2013-10-09 |
| 修稿时间： | 2013-11-30 |
Preparation and Properties of Oleanolic Acid-Alkanolamines Complexes |
| |
| YAN Jiawen,MA Zhenmao. Preparation and Properties of Oleanolic Acid-Alkanolamines Complexes[J]. Chinese Journal of Applied Chemistry, 2014, 31(7): 823-827. DOI: 10.3724/SP.J.1095.2014.30499 |
| |
| Authors: | YAN Jiawen MA Zhenmao |
| |
| Affiliation: | (School of Chemistry and Materials Sciences,Nanjing Normal University,Nanjing 210023,China) |
| |
| Abstract: | Complexes of oleanolic acid(OA) and alkanolamines(EAs)[Ethanolamine(MEA), diethanolamine(DEA)or triethanolamine(TEA)] were prepared by an ultrasonic method. The complexes were characterized by DSC, XRD, IR and Raman spectroscopy. It was found that the complexes is formed through the intermolecular force between OA and EAs rather than chemical bonding. The solubility of OA-EAs complexes is much higher than that of OA. The present study supplies a novel concept for the design of an efficient delivery system of OA. |
| |
| Keywords: | oleanic acid alkanolamines ultrasound method solubility |
| 本文献已被 CNKI 等数据库收录！ |
| 点击此处可从《应用化学》浏览原始摘要信息 |
|
点击此处可从《应用化学》下载全文 |
