Isolation of a potent anti-MRSA sesquiterpenoid quinone from Ulmus davidiana var. japonica |
| |
| Authors: | Shin D Y Kim H S Min K H Hyun S S Kim S A Huh H Choi E C Choi Y H Kim J Choi S H Kim W B Suh Y G |
| |
| Affiliation: | College of Pharmacy, Seoul National University, Kwanak-Gu, Korea. |
| |
| Abstract: | A highly potent anti-MRSA sesquiterpenoid has been isolated from Ulmus davidiana var. japonica, which has been traditionally used to treat infectious diseases in Korea. This naturally occurring antibiotic was identified as mansonone F (1). This compound has been found to be highly active specifically against MRSA and showed an MIC range of 0.39-3.13 microg/ml which is comparable to that of vancomycin. |
| |
| Keywords: | |
| 本文献已被 PubMed 等数据库收录！ |
|
