Determination of long-range distances and dynamic order parameters by dipolar recoupling in high-resolution magic-angle spinning NMR spectroscopy |
| |
Authors: | Thieme Karena Schnell Ingo |
| |
Affiliation: | Max-Planck-Institut für Polymerforschung, and Institut für Organische Chemie, Universit?t Mainz, Germany. |
| |
Abstract: | By introducing dipolar recoupling methods to high-resolution magic-angle spinning (HRMAS) NMR spectroscopy, a class of experiments has been delevoped that allows the measurement of residual dipole-dipole couplings of approximately 1 Hz in weakly immobilized molecules. Using homonuclear 1H-1H recoupling, distances of up to approximately 8 A can be selectively determined, while heteronuclear 1H-13C recoupling provides access to dynamic order parameters of individual molecular segments on the order of approximately 10-3. The experiments are demonstrated on functionalized oligopeptides that are attached to polymer resins. |
| |
Keywords: | |
本文献已被 PubMed 等数据库收录! |
|