Fluorescent profiling of natural product producers |
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| Authors: | Sandler Joel S Fenical William Gulledge Brian M Chamberlin A Richard La Clair James J |
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| Affiliation: | Center for Marine Biotechnology and Biomedicine, Scripps Institution of Oceanography, University of California, San Diego, La Jolla, California 92093-0204, USA. |
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| Abstract: | The identification of natural product producer organisms remains a problem for both isolation and natural product classification. A concise screen is developed through fluorescent modification of a set of natural products that offer a common activity. Through real-time multicolor microscopy, the processing, storage, and effects of a natural product are rapidly screened at the level of the strain and individual organism. |
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