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Structure determination of ramosine, a guaianolide, by NMR spectroscopy
Authors:Khan Sher Bahadar  Afza Nighat  Malik Abdul  ul Haq Azhar  Ahmed Zaheer
Affiliation:International Centre for Chemical Sciences, H.E.J. Research Institute of Chemistry, University of Karachi, Karachi-75270, Pakistan.
Abstract:Ramosine, a new sesquiterpene lactone, was isolated from the chloroform fraction of Amberboa ramosa and the structure was assigned as 4beta-(hydroxymethyl)-3beta,4alpha-dihydroxy-8alpha-[(S)-3-hydroxy-2-ethylenepropionyloxy]-1alphaH, 5alphaH,6betaH,7alphaH,11betaH,11alpha-methylguaia-10(14)-en-6, 12-olide by extensive NMR studies.
Keywords:NMR  1D/2D NMR  ramosine  guaianolide  Amberboa ramosa  Compositae
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