Abstract: | Controlled microwave heating, in particular using sealed‐vessel systems, offers many advantages over traditionally heated syntheses. As most important ones are considered: reduced reaction times, higher yields and reproducibility. In addition, it can rapidly be adapted to a parallel or automated sequential processing format. Because of the convenience of microwave technology and the fact that a “yes or no answer” for a particular chemical transformation can often be obtained within 5 to 10 minutes, this heating method is an efficient tool for many academic and industrial research groups. There it is primarily used for rapid reaction optimization and efficient synthesis of new chemical entities. |