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| 基于SPR原理的葡萄糖浓度折射率特性矩阵测量 | |
| 作者单位： | 1. 中国科学院合肥智能机械研究所，安徽 合肥 230031 2. 中国科学技术大学信息科学与技术学院，安徽 合肥 230026 3. 中国科学院大学电子电气与通信工程学院，北京 100049 |
| 基金项目： | Natural Science Key Foundation, Department of Education, Anhui Province (KJ2016A305); National Science and Technology Support Program (2014BAD08B11) |
| 摘 要： | 设计了一种简洁的角度扫描棱镜SPR传感系统，反射式平行光路设计简化了系统结构。其主要包括光源及光强感知、平行光路结构、电机与温度控制模块构成。通过单电机扫描入射角与温度控制，实现了对葡萄糖的折射率浓度特性有效测量。理论分析存在交叉灵敏度矩阵可同时度量温度及葡萄糖质量浓度共振角度的变化规律，且实验得其灵敏矩阵。为区分温度和质量浓度对共振角度的影响以及校正SPR温度漂移提供参考。 |
| 关 键 词： | 温度 折射率；矩阵测量；平行光路；表面等离子共振 |
| 收稿时间： | 2016-09-01 |
Matrix Measurement of Glucose Concentration Based on Surface Plasmon Resonance Sensor |
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| LUO Wei,SUN Feng-long,LIU Jia-rui,HOU Jun-wu,WANG Ben-gan,HUANG Xiao-ping. Matrix Measurement of Glucose Concentration Based on Surface Plasmon Resonance Sensor[J]. Spectroscopy and Spectral Analysis, 2018, 38(6): 1982-1986. DOI: 10.3964/j.issn.1000-0593(2018)06-1982-05 | |
| Authors: | LUO Wei SUN Feng-long LIU Jia-rui HOU Jun-wu WANG Ben-gan HUANG Xiao-ping |
| Affiliation: | 1. Institute of Intelligent Machines, Chinese Academy of Sciences, Hefei 230031, China2. University of Science & Technology of China, Hefei 230026, China3. University of Chinese Academy of Sciences, Beijing 100049, China |
| Abstract: | An angle scanning prism-based SPR sensor system is proposed in this paper. With the structure of reflex parallel light path, the system has been simplified, which mainly consists of light source, CCD sensor, parallel light path structure, rotation and temperature control module. With the motor scanning incidence angle and temperature control, an effective measurement of glucose refractive index (RI) mass concentration property can be achieved. Moreover, a theoretical model has been established to explain the existence of a sensitivity matrix, which enables both the RI and temperature to be measured and obtained from proof-of-concept experiment. This approach paves a way for conventional SPR-based sensors to discriminate between RI-induced and temperature-induced SPR changes and provides a reference for the correction of temperature interference. |
| Keywords: | Temperature RI Matrix measurement Parallel light path Surface Plasmon Resonance |
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