Development of an accurate procedure for the determination of arsenic in fish tissues of marine origin by inductively coupled plasma mass spectrometry |
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| Institution: | 1. LGC Limited, Queens Road, Teddington, Middlesex, TW11 OLY, UK;1. Department of Chemistry and Institutes of Biomedical Sciences, Fudan University, Shanghai 200433, China;2. Shanghai Key Laboratory of Functional Materials Chemistry, East China University of Science and Technology, Shanghai 200237, China;1. Key Laboratory of Dependable Service Computing in Cyber Physical Society of Ministry of Education, Chongqing University, Chongqing 400044, China;2. College of Automation, Chongqing University, Chongqing 400044, China;3. College of Computer Science, Chongqing University, Chongqing 400044, China;1. Dipartimento di Energia and NEMAS – Center for NanoEngineered Materials and Surfaces, Politecnico di Milano, Via Ponzio 34/3, 20133 Milano, Italy;2. Center for Nano Science and Technology @Polimi, Istituto Italiano di Tecnologia, Via Pascoli 70/3, 20133 Milano, Italy;3. CSIR - National Physical Laboratory, New Delhi 110012, India;1. Orenburg State University, Victory Avenue 13, 460018 Orenburg, Russia;2. Management Company specialized car fleet Ltd., Lugansk Street 5, 460000 Orenburg, Russia;1. Leibniz Institute for Catalysis, A.-Einstein-Str. 29a, 18059 Rostock, Germany;2. Institute for Chemistry, University of Rostock, 18059 Rostock, Germany;1. School of Mathematical Sciences, Anhui University, Hefei 230601, PR China;2. Department of Public Courses, Anhui Xinhua University, Hefei 230088, PR China |
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| Abstract: | High accuracy procedures for the determination of arsenic are needed for assigning reference values to certified reference materials (CRMs). There are a number of problems associated with the determination of total arsenic by inductively coupled plasma–mass spectrometry. Arsenobetaine (AsB) (the major species in fish) gives an enhanced response (9%) when compared to inorganic arsenic(V) and is very difficult to decompose. Chloride causes interference at m/z 75 by the formation of ArCl+ and chloride levels can be significant in marine fish. Also residual carbon in digests can lead to enhancement of arsenic signals by charge transfer effects. This can easily lead to erroneous quantification when compared to standards that do not contain carbon.This newly developed procedure overcomes these issues by complete mineralisation of the matrix leaving insignificant amounts of residual carbon and by removal of chlorine by evaporation. A detection limit of 30 ng/g was achieved. Recoveries for the following CRMs: DORM 2 100.1 ± 4.3%, SRM1548 96.1 ± 4.6%, BCR 422 103.6 ± 6.2% and SRM2976 105.9 ± 6.2% were obtained. The digestion procedure uses open vessel wet digestion with a mixture of sulfuric and nitric acid held at 300 °C. The decomposition of AsB was confirmed by speciation analysis of the digest. Carbon (m/z 13) was monitored to demonstrate the efficiency of the digestion. Instrumentation for the reduction of ArCl+ interference was not required and this view is supported by the recovery data. Measurements were performed by external calibration using tellurium as an internal standard. |
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