Bioactive metabolites from a marine-derived strain of the fungus Neosartorya fischeri |
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| Authors: | Tan Qing-Wei Ouyang Ming-An Shen Shuo Li Wei |
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| Affiliation: | Institute of Plant Virology, Fujian Agriculture and Forestry University, Fuzhou 350002, Fujian, P.R. China. |
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| Abstract: | Two new compounds named fischeacid and fischexanthone, together with eight known compounds, were obtained from the culture of a marine-derived fungus Neosartorya fischeri strain 1008F?. The structures of the new compounds were elucidated based on the spectroscopic data. Bioassays indicated that AGI-B4 and 3,4-dihydroxybenzoic acid showed potent inhibitory effect on the replication of tobacco mosaic virus, and AGI-B4 also possessed an inhibition of the cell proliferation of human gastric cancer cell line SGC-7901 and hepatic cancer cells BEL-7404. |
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