Spectral, magnetic and biological studies of 1,4-dibenzoyl-3-thiosemicarbazide complexes with some first row transition metal ions |
| |
Authors: | Nand K. Singh Saty B. Singh Anuraag Shrivastav Sukh M. Singh |
| |
Affiliation: | (1) Department of Chemistry, Banaras Hindu University, 221 005 Varanasi, India;(2) School of Biotechnology, Banaras Hindu University, 221 005 Varanasi, India |
| |
Abstract: | The ligand 1,4-dibenzoyl-3-thiosemicarbazide (DBtsc) forms complexes [M(DBtsc-H)(SCN)] [M = Mn(II), Co(II) or Zn(II)], [M(DBtsc-H) (SCN)(H2O)] [M = Ni(II) or Cu(II)], [M(DBtsc-H)Cl] [M = Co(II), Ni(II), Cu(II) or Zn(II)] and [Mn(DBtsc)Cl2], which have been characterized by elemental analyses, magnetic susceptibility measurements, UV/Vis, IR,1H and13C NMR and FAB mass spectral data. Room temperature ESR spectra of the Mn(II) and Cu(II) complexes yield values, characteristic of tetrahedral and square planar complexes respectively. DBtsc and its soluble complexes have been screened against several bacteria, fungi and tumour cell lines. |
| |
Keywords: | 3d-Metal complexes thiosemicarbazide antitumour activity |
本文献已被 SpringerLink 等数据库收录! |
|