Quick and highly efficient copper-catalyzed cycloaddition of organic azides with terminal alkynes |
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| Authors: | Wang Dong Zhao Mingming Liu Xiang Chen Yongxin Li Na Chen Baohua |
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| Institution: | State Key Laboratory of Applied Organic Chemistry, Lanzhou University, Lanzhou, 730000, PR of China. |
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| Abstract: | Good to excellent yields of 1,4-disubstituted 1,2,3-triazoles were obtained within 2-25 min when the Cu(I)-catalyzed azide-alkyne cycloaddition (CuAAC) reaction was carried out under solvent-free conditions, with Cu(phen)(PPh(3))(2)]NO(3) (1mol%) as the catalyst. |
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